What is one potential outcome of macrophages presenting antigens to T cells?

Prepare for the University of Central Florida (UCF) MCB3203 Pathogenic Microbiology Exam with comprehensive questions and detailed explanations. Master the concepts necessary to excel in your exam!

The outcome of macrophages presenting antigens to T cells is indeed the activation of the adaptive immune response. When macrophages, a type of antigen-presenting cell, phagocytize pathogens, they process and present antigens on their surface using major histocompatibility complex (MHC) molecules. This presentation is crucial for T cell recognition.

When a T cell recognizes an antigen-MHC complex, it undergoes activation, which is a key step in the adaptive immune response. Activated T cells can then proliferate and differentiate into various subtypes, such as helper T cells that assist in activating B cells for antibody production, and cytotoxic T cells that can kill infected cells. Through this process, macrophages effectively bridge the innate and adaptive immune responses, leading to a more robust and specific response to pathogens.

This understanding highlights the critical role of macrophages in shaping the immune response and why their interaction with T cells is essential for mounting an effective defense against infections.

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